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the official site for ZULRESSO® (brexanolone)
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Sage Therapeutics, Inc. makes no representation as to the information contained on sites we do not own or control. Sage Therapeutics, Inc. does not recommend and does not endorse the content on any third-party websites. Your use of third-party websites is at your own risk and subject to the terms and conditions of use for such sites.
As of January 1, 2025, ZULRESSO® (brexanolone)
is no longer commercially available in the U.S.
Please contact us at Sage Central® Patient Support at 1-844-472-4379
if you have any questions or need more information
What you need to know about
treatment with ZULRESSO
ZULRESSO® (brexanolone) is administered continuously by intravenous infusion (into the vein) over 2.5 days (60 hours). You are treated with Zulresso in a healthcare setting, a Treating Center, where you can be monitored by a healthcare provider throughout your treatment because of the risk of excessive sedation or sudden loss of consciousness.
Because of the risk of serious harm resulting from excessive sedation or sudden loss of consciousness during treatment, ZULRESSO is administered at a Risk Evaluation and Mitigation Strategy (REMS)-certified healthcare facility where you will be monitored by a healthcare provider in accordance with guidelines determined by the ZULRESSO REMS program.
While different Treating Centers may have particular rules and protocols, typically, you'll be able to receive visits from your family and see your baby. However, you will need to arrange for full-time childcare for the duration of your treatment.
Before starting treatment:
- Speak with your healthcare provider about any concerns or questions you have
- Choose someone close to you, like a partner or another loved one, and let them know how they can help during your treatment
Tell your healthcare provider if you take other antidepressants, opioids, or CNS depressants such as benzodiazepines. Keep a list of the medicines you take and show it to your healthcare provider and pharmacist when you get a new medicine. Your healthcare provider will decide if other medicines can be taken with ZULRESSO.
Please remember that your healthcare provider and the team at your Treating Center should always be your primary resources for any questions regarding your treatment.
We are here for you
Sage Central is a source for patient support resources and information. Once enrolled, you will have a dedicated team of support specialists—known as Sage Central Navigators—who can provide information to help you throughout your treatment journey with ZULRESSO.
After you sign up with Sage Central, a Navigator will call you within 1 to 2 business days to welcome you, begin to guide you through the treatment process, and provide helpful information.
How can our Navigators help? They can:
- Answer questions about ZULRESSO and the treatment process
- Explain your insurance benefits and coverage options
- Provide information to help you prepare for your infusion
- Review financial assistance programs for eligible patients
Contact us for more information about treatment with ZULRESSO for postpartum depression (PPD) or assistance with enrolling in Sage Central. You can also find additional patient support programs offered by Sage Central by visiting our website.
Financial support
Sage Central Navigators can direct eligible patients to financial assistance for their ZULRESSO treatment. Eligible commercially insured patients may pay as little as $0.* Learn about the ZULRESSO Drug Copay Assistance Program, ZULRESSO Infusion Copay Assistance Program, and Free Drug Program.
